Cambered pavements as a chronic metabolic stressor: the complete molecular cascade from asymmetric joint loading to systemic ageing markers, intervention timing, and the clinical framework. By Dr Dima Martini-Drew MD.
What happens when you trace the biomechanical insult of environmental gradients all the way through to its metabolic and epigenetic consequences. The answer implicates infrastructure policy as a direct determinant of biological ageing.
